Duke University | Pratt School of Engineering

SERS Plasmonic Chips

In 1984, our laboratory first reported the general applicability of SERS as an analytical technique [Analytical Chemistry, 56: 1667 (1984)]. We also first introduced the use of metal film on nanostructures (MFON), referred to as 'nanowave', as efficient and reproducible plasmonics-active media. Read more

Nanobiosensors

In 2000, our laboratory developed the first antibody-based nanobiosensor for monitoring biochemical species in a single living human cell [Nature Biotechnology, 18: 764-767 (2000)]. Various nanobiosensors were later developed for monitoring intracellular parameters... Read more

THERANOSTICS: Two-photon Photoluminescence Imaging & Photothermal Therapy

Two-photon photoluminescence (TPL) imaging offers a strong optical contrast mechanism for viewing Gold Nanostars in real-time. Read more

 

Gold Nanostar for Molecular Imaging and Cancer Therapy

Gold nanostars exhibit a unique star shape and several interesting photonic properties that can be exploited for molecular imaging and cancer therapy. Read more

THERANOSTICS: SERS Detection & Photodynamic Therapy

The use of NIR Raman dye labeled nanostar with the photosensitizer methylene blue (MB) encapsulated in a silica shell around the particle is promising for theranostic applications. Read more 

SERS Molecular Probes

In 1994 our laboratory first introduced a new modality for nucleic acid bioassays using SERS detection [Analytical Chemistry, 66, 3379 (1994)]. We further extended the new family of SERS gene probes with the development of ‘Molecular Sentinels’ and Plasmonic Coupling Interference (PCI)... Read more

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The Vo-Dinh Lab is a part of the Department of Biomedical Engineering of the Pratt School of Engineering, and the Chemistry Department of the School of Arts & Science,  Duke University. Together with a number of other research groups, the Vo-Dinh Lab is also a part of the Fitzpatrick Institute for Photonics, of which Professor Vo-Dinh is the director.

Research Focus:

The research of the Vo-Dinh Lab is focused on the development of advanced technologies for the protection of the environment and the improvement of human health. The research activities involve biophotonics, nanoplasmonics, nanosensors, laser spectroscopy, molecular imaging, medical diagnostics, cancer detection and therapy, theranostics, chemical sensors, biosensors, and biochips.

Our laboratories are located in the Fitzpatrick Center (FCIEMAS) and the French Family Science Center, both situated on Duke University West Campus.

FCIEMAS

Fitzpatrick Center (FCIEMAS)

 

French

French Family Science Center